Hypercell utilizes electro-select chips containing 16 channels for cell identification and sorting based on secretion. Using computer vision, it allows for separating complex/mixed samples into populations of cells that secrete your desired antibody in the format of dark clusters for high secretion to low or none. Our computer software can be set with specific criteria for high purity requirements or high throughput requirements to suit your specific needs.
Our bench-top system and DR-S consumables can accelerate and simplify the drug discovery process by identifying and isolating high antibody producing single B cells.
Our bench-top system and DR-N consumables can accelerate and simplify the cell line development process by identifying and isolating high antibody producing single CHO cells to increase the resulting titer.
Perform direct single B cell screening with no hybridoma fusion. Find your functional cells of interest faster and accelerate your drug discovery process with Hypercell.
Hypercell’s Specific Detection Reagents (DR-S Caption), enables rapid detection and sorting of single cells, including primary B cell screens. Find high secreting antibodies faster while reducing the cost of bringing new therapies to the clinic. Hypercell enables direct B cell and spleenocyte screening, avoiding hybridoma screening, in two days vs. three weeks.
Cell Line Developers Hypercell Non-Specific Detection Reagents (DR-N Caption), enables rapid isolation of high producing cells following transfection.
An example of CHO Cell Line Development for mAb production is illustrated here.