Key advantages of Bioelectronica’s Hypercell™ platform are throughput, scalability, rapid detection and cell recoverability. Through a combination of multiple proprietary innovations, Hypercell™ takes emulsion-based single-cell assays to the next level. With PODS technology, millions of cells can be encapsulated in minutes, versus hours required by serial droplet generators. Hypercell™ is well suited for ultra-high throughput applications such as cell line development in immunology and vaccine development. The Hypercell platform can be parallelized to scale up experiments and dramatically increase lab productivity, throughput and efficiencies.
Hypercell™-Analytix lets you visualize the relative secretion rate of hundreds of thousands of cells within a sample — and with antigen-specific single cell secretion rates.
By combining Bioelectronica’s reagent kits and patent-pending imager, Hypercell™ Analytix can calculate the ratio of cells secreting high, medium and low amounts of a specific antigen, antibody or protein that is normalized to the size of each individual POD.
The technology can be applied across many types of experiments including CAR-T construct screening and validation, antigen or T cell receptor discovery and validation, as well as investigation of helper or regulatory T cell function.
Antibody manufacturers can monitor their bioreactors over time. Antibody developers can monitor the stability of their CHO or HEK 293 cells and use Analytix to help them choose when to move to the next stage of their cell line development path.
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